Cutting Edge: Induction of Follicular Homing

Precedes Effector Th Cell Development Cutting Edge: Induction of Follicular Homing

Receptor Dependence by Mucosal Effector B Cutting Edge: Dichotomy of Homing

Experimental Study of the Effect of Laser-Cutting Process Parameters on Heat Distribution and Cutting Edge Quality of Steel Sheets

This study aimed to evaluate Laser-cutting process of Mild Steel St37 sheets with two different thicknesses. In order to evaluate the quality of cutting edge and the depth of the area affected by the heat, several tests were conducted to determine the effect of parameters such as Laser power, Laser beam movement speed and pressure of axillary gas on the quality of cutting edge and the depth of ...

Cutting Edge Cutting Edge: Instructive Role of Peripheral Tissue Cells in the Imprinting of T Cell Homing Receptor Patterns

Tissue-specific homing of effector and memory T cells to skin and small intestine requires the imprinting of specific combinations of adhesion molecules and chemokine receptors by dendritic cells in the draining lymph nodes. In this study, we demonstrate that CD8 T cells activated by Ag-pulsed bone marrow-derived dendritic cells were induced to express the small intestine homing receptors 4 7 i...

Cutting Edge: Distinct waves of BCL6 expression during T follicular helper cell development.

T follicular helper (T(FH)) cells are central to the development and regulation of T cell-dependent humoral immune responses. The transcriptional repressor BCL6 is required for T(FH) responses, but the kinetics of BCL6 protein expression in activated CD4(+) T cells have not been established. We measured BCL6 expression during T(FH) cell development at the single-cell level using intracellular s...